Canderin 16mg tablets
Ingredients in every tablet
Each package contains
|ATC Level 1||C - Cardiovascular system|
|ATC Level 2||C09 - Agents Acting on the Renin-Angiotensin System|
|ATC Level 3||C09C - Angiotensin II Receptor Blockers (Arbs); Plain|
0 TO 18 YEARS OLD
The safety and efficacy of candesartan have not been established in children and adolescents (under 18 years).
18 TO 65 YEARS OLD
— Dosage in hypertension:
The initial dose is 4 mg once daily. The dose should be adjusted according to response, with a maximum dose of 16 mg daily. The maximum effect is achieved within about 4 weeks after initiating therapy.
— Dosage in heart failure:
The usual recommended initial dose is 4 mg once daily. Up-titration to the target dose of 32 mg once daily or the highest tolerated dose is done by doubling the dose at intervals of at least 2 weeks.
65 YEARS OLD AND ABOVE
No initial dosage adjustment is necessary in elderly patients.
Candesartan should be taken once daily with or without food. Candesartan can be administered with other antihypertensive drugs.
PATIENTS WITH HEPATIC IMPAIRMENT
An initial dose of 2 mg once daily is recommended in patients with mild to moderate hepatic impairment. The dose may be adjusted according to response. There is no experience in patients with severe hepatic impairment.
PATIENTS WITH RENAL IMPAIRMENT
No initial dosage adjustment is necessary in mild renal impairment. A lower initial dose of 2 mg once daily is suggested for patients with moderate and severe renal impairment. The dose may be adjusted according to response.
Treatment of hypertension.
Treatment of patients with heart failure and impaired left ventricle systolic function (left ventricular ejection fraction ≤ 40%) when ACE-inhibitors are not tolerated.