Lepsio syrup
Dexa Medica
Ingredients in every 5 ml
| Valproic Acid | 250 mg |
Each package contains
Other details
| Flavour | None |
W.H.O. classification
| ATC Level 1 | N - Nervous system |
| ATC Level 2 | N03 - Antiepileptics |
| ATC Level 3 | N03A - Antiepileptics |
Warnings
Pregnancy
Lactation
Alcohol
Machinery
Available in
 |
Indonesia |
 |
The Philippines |
Dosage information
FOR ALL AGES
LEPSIO is administered orally. The recommended initial dose is 15 mg/kg/day, increasing at one week intervals by 5 to 10 mg/kg/day, until seizures are controlled or side effects preclude further increases.
The maximum recommended dosage is 60 mg/kg/day. If the total daily dose exceeds 250 mg, it should be given in a divided regimen.
PEDIATRIC USE
Hepatotoxicity appears to be more common in children, especially those under 2 years and those taking multiple antiepileptic drugs. The drug should be used with extreme caution and as single-agent therapy in such children, and the benefits of valproic acid therapy weighed against the risks.
Indication
Valproic acid may be used as sole or adjunctive therapy in the treatment of partial seizures (both elementary and complex) and absence seizures (petit mal seizures).