Medixon 500mg powder for injection
Ferron Par Pharmaceuticals
Ingredients in every 8 ml
| Methylprednisolone | 500 mg |
Each package contains
Other details
| Flavour | None |
W.H.O. classification
| ATC Level 1 | H – Systemic hormonal preparations; excluding sex hormones and insulins |
| ATC Level 2 | H02 – Corticosteroids for Systemic Use |
| ATC Level 3 | H02A – Corticosteroids for Systemic Use; Plain |
Warnings
Pregnancy
Lactation
Alcohol
Machinery
Available in
 |
Indonesia |
Dosage information
UP TO 18 YEARS
— Adrenocortical insufficiency:
Intramuscular, 0.18 mg (base) per kg of body weight or 3.33 mg (base) per square meter of body surface area daily (in three divided doses) every third day
— Acute spinal cord injury treatment:
Intravenous, 30 mg (base) per kg of body weight administered over a 15 minutes, followed after 45 minutes by a continuous infusion of 5.4 mg per kg of body weight per hour, for 23 hours.
— Adjunctive treatment in patients with Pneumocystis carinii pneumonia associated with AIDS:
Children up to 14 years of age: dosage has not been established.
Children 14 years of age or older: see Adults and adolescents dose.
18 YEARS OLD AND ABOVE
IM/IV 10 –40 mg (base), repeated as needed
High dose (pulse therapy): IV, 30 mg (base) per kg of body weight administered over at least 30 minutes. This dose may be repeated every 4-6 hours for 48 hours.
— Acute exacerbations of multiple sclerosis:
Intramuscular or intravenous, 160 mg (base) daily for 1 week, followed by 64 mg (base) every other day for 1 month
— Acute spinal cord injury treatment:
Intravenous, 30 mg (base) per kg of body weight administered over 15 minutes, followed after 45 minutes by a continuous infusion of 5.4mg per kg of body weight per hour, for 23 hours.
— Adjunctive treatment in patients with Pneumocystis carinii pneumonia associated with AIDS:
Intravenous,
– 30 mg (base) twice daily on days one through five,
– 30 mg once daily on days six through ten, and
– 15 mg once daily on days eleven through twenty one.
DIRECTIONS FOR USE
IM or IV injection:
Reconstitute powder by adding solvent (containing benzyl alcohol 0.9%), mix homogeneously. Direct intravenously can be given at least 1 minute or can be given by intravenously infusion in dextrose 5%, NaCl 0.9% or dextrose 5% in NaCl 0.9% for at least 30 minutes. The solution is stable physically and chemically for 48 hours.
Indication
Endocrine disorders, allergic disorders, collagen disorders, dermatologic disorders, gastrointestinal disorders, hematologic disorders, hepatic diseases, nonrheumatoid inflammation, neoplastic diseases, nephrotic syndrome, neurologic diseases, neurotrauma, ophthalmic disorders, pericarditis, nasal polyps, respiratory disorders.