Ferron Par Pharmaceuticals
Ingredients in every 10 ml
|Glyceryl Trinitrate||1 mg|
Each package contains
|ATC Level 1||C - Cardiovascular system|
|ATC Level 2||C01 - Cardiac Therapy Drugs|
|ATC Level 3||C01E - Other Cardiac Preparations in ATC|
18 YEARS OLD AND ABOVE
The recommended dosage range is 10-200 μg/minute but up to 400 μg/minute may be necessary during some surgical procedures.
Glyceryl trinitrate solution is a concentrate which should be diluted prior to IV administration. The product is normally administered IV as an admixture using a suitable vehicle such as 5% dextrose or 0.9% sodium chloride injection
Glyceryl trinitrate is incompatible with polyvinylchloride (PVC) and severe loses of glyceryl trinitrate (over 40%) may occur if this material is used. Contact with PVC bags should be avoided.
A starting dose of 25 μg/minute is recommended for the control of hypertension, or to produce hypotension during surgery. This may be increased by increments of 25 μg/minute at 5-minute intervals until the blood pressure is stabilized. Doses between 10-200 μg are usually sufficient during surgery, although doses of up to 400 μg/minute have been required in some cases.
UNRESPONSIVE CONGESTIVE HEART FAILURE
The recommended starting dose is 20-25 μg/minute. This may be decreased to 10 μg/minute or increased in steps of 20-25 μg/minute every 15-30 minutes until the desired effect is obtained.
An initial dose of 10 μg/minute is recommended, with increments of 10 μg/minute being made at approximately 30 minute intervals according to the needs of the patien
– The rapid control of hypertension during cardiac surgery. (I p.1, II p.537, III p.1, IV p.1, V p.2178, VI p.1798, VII p.N118, VIII p.1297)
– Reducing blood pressure and maintain controlled hypotension during surgical procedures. (II p.537, III p.1, IV p.1, V p.2178, VI p.1798, VIII p.1297)
– Controlling myocardial ischemia during and after surgery. (II p.537, III p.1, IV p.1)
• Unresponsive congestive heart failure secondary to acute myocardial infarction. (I p.1, II p.537, III p.1, IV p.1, V p.2178, VI p.1798, VII p.N118, VIII p.1297)
• Unstable angina which is refractory to treatment with beta blockers and sublingual nitrates. (I p.1, II p.537, III p.1, IV p.1, V p.2178, VI p.1798, VII p.N118, VIII p.1298)