Prezinton injection

Dexa Medica

Ingredients in every ml

Ondansetron 2 mg

Each package contains

2 ampoules of 4 ml

Other details

Dosage form:Injection
Flavour None

W.H.O. classification

ATC Level 1 A - Alimentary tract and metabolism
ATC Level 2 A04 - Antiemetics and Antinauseants
ATC Level 3 A04A - Antiemetics and Antinauseants

Warnings

Pregnancy

NOT SAFEThis item is not safe for use during pregnancy.

Lactation

NOT SAFEThis item is not safe for use during lactation.

Alcohol

CONSULT YOUR DOCTORSafety of this item for use with alcohol has not been established. Please consult your doctor.

Machinery

SAFE IF PRESCRIBEDThis item is safe for use while operating heavy machinery.

Available in

Myanmar

Dosage information

18 TO 65 YEARS OLD
Prevention of nausea and vomiting associated with chemotherapy:
• Highly emetogenic chemotherapy, e.g. cisplatin.
Initially PREZINTON may be given as a slow IV injection of 8 mg single dose or 15 minutes infusion of 8 mg immediately before chemotherapy. The alternative dose of ondansetron may be administered as a slow IV or IM injection of 8 mg immediately before chemotherapy, followed by two further IV or IM doses of 8 mg 2 to 4 hours apart, or by a constant infusion of 1 mg/hour for up to 24 hours. Either regimen is then followed by 8 mg orally 12 hourly for up to 5 days.

• Less emetogenic chemotherapy, e.g. cyclophosphamide.
PREZINTON 8 mg may be administered as a slow IV or IM injection or 15 minutes infusion of 8 mg immediately before chemotherapy, followed by 8 mg orally, twice daily for less than 5 days.

Prevention of postoperative nausea and vomiting:
The recommended dose of ondansetron injection is a single dose of 4 mg may be given as a slow IV or IM injection.

4 TO 18 YEARS OLD
Prevention of nausea and vomiting associated with chemotherapy:
• PREZINTON may be administered as a single IV dose of 5 mg/m2 body area (0.15 mg/kg) for 15 minutes immediately prior to chemotherapy, ) followed by 4 mg orally every 12 hours for less than 5 days.

Prevention of postoperative nausea and vomiting:
The recommended dose of ondansetron injection is a single dose of 4 mg may be given as a slow IV or IM injection.

0 TO 2 YEARS OLD
PREZINTON should not be used

Prevention of postoperative nausea and vomiting:
The recommended dose of ondansetron injection is a single dose of 4 mg may be given as a slow IV or IM injection.

65 YEARS OLD AND ABOVE
Ondansetron is well tolerated in patients over 65 years without dosage adjustment, frequency and method of administration.

Prevention of postoperative nausea and vomiting:
The recommended dose of ondansetron injection is a single dose of 4 mg may be given as a slow IV or IM injection.

IMPAIRED HEPATIC FUNCTION
In such patients a total daily dose of 8 mg ondansetron should not be exceeded.

Indication

Treatment and prevention of nausea and vomiting associated with chemotherapy, radiotherapy and surgery.