Sevodex inhalation vapour
Ingredients in every vial
Each package contains
|ATC Level 1||N – Nervous system|
|ATC Level 2||N01 – Anesthetics|
|ATC Level 3||N01A – Anesthetics; General|
FOR ALL AGES
The concentration of sevoflurane being delivered from a vaporizer during anesthesia should be known. This may be accomplished by using a vaporizer calibrated specifically for sevoflurane. The administration of general anesthesia must be individualized based on the patient’s response.
Replacement of desiccated CO₂ absorbents
When a clinician suspects that the CO₂ absorbent may be desiccated, it should be replaced. The exothermic reaction that occurs with sevoflurane and CO2 absorbents is increased when the CO₂ absorbent become desiccated, such as after an extended period of dry gas flow through the CO₂ absorbent canisters.
Pre-medication should be selected according to the needs of the individual patient, and at the discretion of the anaesthetist.
Sevoflurane has a non-pungent odor and does not cause respiratory
irritability; it is suitable for mask induction in pediatrics and adults. Sevoflurane is given in concentrations of up to 5% in adults and 8% in children, with oxygen or a mixture of oxygen and nitrous oxide. Induction with sevoflurane is rapid (surgical anaesthesia in less than 2 minutes).
Surgical levels of anesthesia can usually be achieved with concentrations of 0.5 - 3% sevoflurane with or without the concomitant use of nitrous oxide. Sevoflurane can be administered with any type of anesthesia circuit.
MAC (minimum alveolar concentration) values for adults and pediatric patients according to age:
0-1 month (Neonates are full-term gestational age. MAC in premature infants has not been determined.)
Sevoflurane in oxygen= 3.3%
Sevoflurane in 65% N₂O/35% O₂= -
1- <6 months Sevoflurane in oxygen= 3.0% Sevoflurane in 65% N₂O/35% O₂= - 6 months - < 3 years Sevoflurane in oxygen= 2.8% Sevoflurane in 65% N₂O/35% O₂= 2.0% (In 1 - < 3 year old pediatric patients, 60% N₂O/40% O₂ was used.) 3 -12 years Sevoflurane in oxygen= 2.5% Sevoflurane in 65% N₂O/35% O₂= 25 years Sevoflurane in oxygen= 2.6% Sevoflurane in 65% N₂O/35% O₂= 1.4% 40 years Sevoflurane in oxygen= 2.1% Sevoflurane in 65% N₂O/35% O₂= 1.1% 60 years Sevoflurane in oxygen= 1.7% Sevoflurane in 65% N₂O/35% O₂= 0.9% 80 years Sevoflurane in oxygen= 1.4% Sevoflurane in 65% N₂O/35% O₂= 0.7%
Sevoflurane is indicated for induction and maintenance of general anesthesia in Adults and pediatric patients for inpatient and outpatient surgery.