DUODENAL ULCER, GASTRIC ULCER, REFLUX ESOPHAGITIS
The recommended intravenous dosage is one vial (40 mg pantoprazole) per day.
ZOLLINGER-ELLISON SYNDROME & OTHER PATHOLOGICAL HYPERSECRETORY CONDITIONS
Patients should start their treatment with a daily dose of 80 mg pantoprazole IV. Thereafter, the dosage can be titrated up or down as needed using measurements of gastric acid secretion to guide. With doses above 80 mg daily, the dose should be divided and given twice daily. A temporary increase of the dosage above 160 mg pantoprazole is possible but should not be applied longer than required for adequate acid control. Transition from oral to IV and from IV to oral formulations of gastric acid inhibitors should be performed in such manner to ensure continuity of effect of suppression of acid secretion.